Sensitivity analysis (SA) is en route to becoming an integral part of mathematical modeling. The tremendous potential benefits of SA are, however, yet to be fully realized, both for advancing mechanistic and data-driven modeling of human and natural systems, and in support of decision making. In this perspective paper, a multidisciplinary group of researchers and practitioners revisit the current status of SA, and outline research challenges in regard to both theoretical frameworks and their applications to solve real-world problems. Six areas are discussed that warrant further attention, including (1) structuring and standardizing SA as a discipline, (2) realizing the untapped potential of SA for systems modeling, (3) addressing the computational burden of SA, (4) progressing SA in the context of machine learning, (5) clarifying the relationship and role of SA to uncertainty quantification, and (6) evolving the use of SA in support of decision making. An outlook for the future of SA is provided that underlines how SA must underpin a wide variety of activities to better serve science and society. • Sensitivity analysis (SA) should be promoted as an independent discipline. • Several grand challenges hinder full realization of the benefits of SA. • The potential of SA for systems modeling & machine learning is untapped. • New prospects exist for SA to support uncertainty quantification & decision making. • Coordination rather than consensus is key to cross-fertilize new ideas.

To advance monitoring of surface water resources, new remote sensing technologies including the forthcoming Surface Water and Ocean Topography (SWOT) satellite (expected launch 2022) and its experimental airborne prototype AirSWOT are being developed to repeatedly map water surface elevation (WSE) and slope (WSS) of the world’s rivers, lakes, and reservoirs. However, the vertical accuracies of these novel technologies are largely unverified; thus, standard and repeatable field procedures to validate remotely sensed WSE and WSS are needed. To that end, we designed, engineered, and operationalized a Water Surface Profiler (WaSP) system that efficiently and accurately surveys WSE and WSS in a variety of surface water environments using Global Navigation Satellite Systems (GNSS) time-averaged measurements with Precise Point Positioning corrections. Here, we present WaSP construction, deployment, and a data processing workflow. We demonstrate WaSP data collections from repeat field deployments in the North Saskatchewan River and three prairie pothole lakes near Saskatoon, Saskatchewan, Canada. We find that WaSP reproducibly measures WSE and WSS with vertical accuracies similar to standard field survey methods [WSE root mean squared difference (RMSD) ∼8 cm, WSS RMSD ∼1.3 cm/km] and that repeat WaSP deployments accurately quantify water level changes (RMSD ∼3 cm). Collectively, these results suggest that WaSP is an easily deployed, self-contained system with sufficient accuracy for validating the decimeter-level expected accuracies of SWOT and AirSWOT. We conclude by discussing the utility of WaSP for validating airborne and spaceborne WSE mappings, present 63 WaSP in situ lake WSE measurements collected in support of NASA’s Arctic-Boreal and Vulnerability Experiment, highlight routine deployment in support of the Lake Observation by Citizen Scientists and Satellites project, and explore WaSP utility for validating a novel GNSS interferometric reflectometry LArge Wave Warning System.