Angewandte Chemie International Edition, Volume 59, Issue 9
- Anthology ID:
- G20-16
- Month:
- Year:
- 2020
- Address:
- Venue:
- GWF
- SIG:
- Publisher:
- Wiley
- URL:
- https://gwf-uwaterloo.github.io/gwf-publications/G20-16
- DOI:
Target Self‐Enhanced Selectivity in Metal‐Specific DNAzymes
Po‐Jung Jimmy Huang
|
Donatien de Rochambeau
|
Hanadi F. Sleiman
|
Juewen Liu
The more the merrier: Better selectivity for Zn2+ ions is shown for DNAzymes that bind more metal ions. This selectivity is exemplified by using a series of in vitro selected DNAzymes that contain a single metal ligand modification at the cleavage junction.